PENGGUNAAN ANTIHIPERTENSI PADA PASIEN STROKE NON HEMORAGIK DI INSTALASI FARMASI RAWAT JALAN RUMAH SAKIT X SEMARANG

  • Paulina Maya OCTASARI
  • Anastasia Veny OKTAVIANI
Keywords: Non-Hemorrhagic Stroke, Antihypertensive Agent, Pharmaceutical Installations In Hospital X Semarang

Abstract

Non-hemorrhagic stroke is a functional disorder of the brain’s neurologic deficits caused by vasocontraction due to blockage in the arterial vessel leading to the brain. There were 79% of non-hemorrhagic stroke patients are caused by hypertension. Antihypertensive therapy for the patients given as secondary therapy to prevent recurrent stroke, decreased brain edema risk, hemorrhagic risk, and prevent further vascular damage. Therefore this research aimed to evaluate antihypertensive usage in non-hemorrhagic stroke patients in the Hospital. The research is an observational descriptive with cross-sectional design and retrospective data. Data retrieval through the medical record of outpatients with ages 36-65 years were diagnosed with non-hemorrhagic stroke with or without comorbidities and National Health Insurance patients period of October - December in 2019. Data were classified based on age, gender, and antihypertensive agent, and were analyzed by calculating the percentage of patients who have decrease, stability, and increased blood pressure. 92 patients who were included in the inclusion criteria. The result showed that more male patients (68,48%), mostly age category 55-65 years (70,65%) with hypertensive (51,09%). Antihypertensive usage in non-hemorrhagic stroke is mostly used CCB group (70,65%). The percentage of patients who suffered a decrease in systolic blood pressure as much as 53 patients (57,6%), meanwhile the decrease in diastolic blood pressure as much as 63 patients (68,46%). There were 69 patients (75%) has blood pressure target therapy.

References

Budiman, Sihombing, R., dan Pradina, P.

Hubungan Dislipidemia,

Hipertensi, Dan Diabetes Melitus

Dengan Kejadian Infark Miokard

Akut. Jurnal Kesehatan Masyarakat

Andalas. Vol 10 No 1. 32-37

Chiburdanidze, A., 2013. Evaluasi

Ketepatan Pemilihan Obat dan

Outcome Terapi pada Pasien

Hipertensi Rawat Jalan di Rumah

Sakit A Tahun 2013. Skripsi.

Fakultas Farmasi Universitas

Muhammadiyah. Surakarta.

Damayanti, F., 2014. Hubungan Tingkat

Kepatuhan Penggunaan Obat

Terhadap Keberhasilan Terapi pada

Pasien Hipertensi di Rumah Sakit X

Surakarta Bulan Mei – Juni 2014.

Skripsi. Fakultas Farmasi Universitas

Muhammadiyah. Surakarta

Dipiro, J. T., Wells, B.G.,

Schwinghammer, T.L., Dipiro, C.V.,

Pharmacoterapy Handbook,

th ed. McGraw-Hill Education,

United States.

Fadhila, S.N., and Permana, D., 2020. The

Use Of Antihypertensive Drugs In

The Treatment Of Essential

Hypertension At Outpatient

Installation Puskesmas Karang Rejo.

Yarsi Journal of Pharmacology.Vol

No 1. 7 – 14

Fagan, S.C., and Hess, D.C., 2008. Stroke.

In: Wells, Barbara G., Dipiro,

J.T.Schwinghammer,T.L. and Dipiro,

C.V. A Pharmacotherapy:

Pathophysiologic Approach, 7th Ed.

New York: The McGraw Hills, 373-

Herawati, and Sartika, W. 2013.

Terkontrolnya Tekanan Darah

Penderita Hipertensi Berdasarkan

Pola Diet Dan Kebiasaan Olah Raga.

Jurnal Kesehatan Masyarakat Vol. 8

No. 1, 8 – 14

Ikawati, Z. 2011. Farmakoterapi Penyakit

Sistem Saraf Pusat. Yogyakarta:

Bursa Ilmu.

Irianto, K., 2018, Anatomi dan Fisiologi,

Bandung: Alfabeta.

JNC VII. 2003. The Seventh Report of the

Joint National Committe on

Prevention, Dectection, Evaluation,

and Treatment of High Blood

Pressure.

Junaidi, I., 2011. Stroke Waspadai

Ancamannya. Yogyakarta : ANDI

Karuniawati, H., Ikawati, Z., Gofir, A.,

, Pencegahan Sekunder untuk

Menurunkan Kejadian Stroke

Berulang pada Stroke Iskemik.

Jurnal Manajemen dan Pelayanan

Farmasi (JMPF); Vol. V No.1, 8 –

Kemenkes RI, 2013. Riset Kesehatan

Dasar tahun 2013. Kementrian

Recived : 15 – 08 – 2020

Accepted : 02 – 10 – 2020

Published : 30 – 10 – 2020

kesehatan Republik Indonesia.

Jakarta

Meschia, J. F., Bushnell, C., Albala, B. B.,

Braun, L. T., Bravata, D. M.,

Chaturvedi, S., et al. (2014).

Guidelines for the Primary

Prevention of Stroke: A Statement

for Healthcare Professionals From

the American Heart

Association/American Stroke

Association. Stroke, 3754–3832.

Munir B, Rasyid HA, Rosita R (2015).

Hubungan Antara Kadar Glukosa

Darah Acak Pada Saat Masuk

Instalasi Gawat Darurat Dengan

Hasil Keluaran Klinis Penderita

Stroke Iskemik Fase Akut. MNJ.

(2). 62 – 60

Ramadany, A.F., Pujarini, L.A.,

Candrasari, A., 2013. Hubungan

Diabetes Melitus dengan Kejadian

Stroke Iskemik di RSUD Dr.

Moewardi Surakarta. Biomedika,

Volume 5 Nomor 2, 11 – 16.

Sihombing, M., 2017. Faktor Yang

Berhubungan Dengan Hipertensi

Pada Penduduk Indonesia Yang

Menderita Diabetes Melitus (Data

Riskesdas 2013).

http://dx.doi.org/10.22435/bpk.v45i1

.5730.53-64.

Waris, L., Liberty, I.A., Pariyana., Roflin.

E., 2017. Determinan Kepatuhan

Berobat Paien Hipertensi pada

Fasilitas Kesehatan Tingkat I.

Volume 1 Nomor 1. 58 – 65

Watila M. M., Nyandaiti Y. W., Ibrahim

A., Balarabe S. A., Gezawa I. D.,

Bakki B., Tahir A., Sulaiman M.

M. and Bwala S. A., 2012. Risk

Factor Profile Among Stroke Patient

In Northeastern Nigeria. Journal

neuroscience and behavioural

health, 4(5), 50-58.

Zhang, MD., Song, MD., Xu, MD. 2017.

Effectiveness And Safety Of

Valsartan Or Amlodipine In

Hypertensive Patient With Stroke.

Medicine (Baltimore). 96:26, 1 – 6,

doi:10.1097/MD.0000000000007172

Published
2020-10-30
How to Cite
Maya OCTASARI, P., & Veny OKTAVIANI, A. (2020). PENGGUNAAN ANTIHIPERTENSI PADA PASIEN STROKE NON HEMORAGIK DI INSTALASI FARMASI RAWAT JALAN RUMAH SAKIT X SEMARANG. Media Farmasi Indonesia, 15(2), 1604-1610. https://doi.org/10.53359/mfi.v15i2.161