ANALISIS EFEKTIVITAS BIAYA PENGOBATAN DEMAM TIFOID PADA ANAK MENGGUNAKAN ANTIBIOTIK KLORAMFENIKOL DAN SEFIKSIM (STUDI OBSERVASI ANALITIK DI RUMAH SAKIT ISLAM SULTAN AGUNG SEMARANG. PERIODE JANUARI – DESEMBER 2015
Abstract
ABSTRACT
Background: Typhoid fever is an acute infectious disease of the gastrointestinal tract caused by Salmonella Typhi. This disease ranks third among the most prevalent diseases pattern 10 inpatients at the hospital in 2006 with the number of 72 804 patients (3:26%) (MOH, 2007). Chloramphenicol antibiotic treatment is very cost effective for the treatment of typhoid fever in children and for antibiotics cefixime proved to be good and effective. This study aims to determine the cost-effectiveness of treatment of typhoid fever in children in the Islamic Hospital Sultan Agung Semarang period from January to December, 2015
Metod : This type of research is analytic observational retrospective approach. The research sample is taken from a medical record inpatient Islamic Hospital Sultan Agung Semarang period from January to December 2015 have met the inclusion criteria, data analysis using ACER value calculation is the total cost of treatment is divided by the length of stay.
Result :The results showed that 53 samples obtained in room B. Nisa '2 of the 31 medical records of patients with a diagnosis of typhoid fever that using antibiotics chloramphenicol and cefixime, and room B. Nisa' 3 at 22 medical records of patients with a diagnosis of typhoid fever that using antibiotics chloramphenicol and cefixime
Conclusion :Treatment of typhoid fever in children with antibiotics chloramphenicol is more cost effective than the antibiotic cefixime therapy group. Antibiotic chloramphenicol in Space Baitun Nisa '2 have the cost effectiveness of treatment with ACER value of USD 376 775 / day and for room Baitun Nisa' 3 Rp 296 980 / day
References
Adisasmito, A. W., 2006, Penggunaan
antibiotik pada terapi demam tifoid
anak di RSAB Harapan Kita.Sari
Pediatri; 8: 174-80.
Andayani, T. M., 2013, Farmakoekonomi:
Prinsip dan Metodologi, Bursa Ilmu,
Yogyakarta
Bahn, M. K., Bahl, R., Bhatnagar, S.,
, Typhoid and Paratyphoid
Fever, All India Institute of Medical
Sciences, New Delhi 110029, India.p
-15
Berger, M. L., Bingefors, K., Hedblom, E.,
Pashos, C. L., Torrance, G., Smith,
M. D., 2003, Health Care Cost,
Quality, and Outcomes: ISPOR Book
of Terms, ISPOR: USA
Bhutta, Z. A., 2011, Enteric fever (Typhoid
Fever), In: Nelson Text Book of
Pediatric, 19th edition, Philadelphia:
Elsevier Saunders, p.954-958.
Bootman, J. L., Townsend, R. J., dan
McGhan, W. F., 2005, Principles of
Pharmacoeconomics, 3rd Ed., 1-18,
Harvey Whitney Book
Company,USA
Budiharto, M., dan Kosen, S., 2008,
Peranan Farmako-Ekonomi Dalam
Sistem Pelayanan Kesehatan Di
Indonesia, Pusat Penelitian dan
Pengembangan Sistem Dan
Kebijakan Kesehatan. Vol. 11 No. 4,
-340
Chamber, H. F., 2011, Obat
Kemoterapetik, Edisi 10, Jakarta:
EGC.
Depkes RI, 2007, Profil Kesehatan
Indonesia 2005, Jakarta
Depkes RI, 2008, Profil Kesehatan
Indonesia 2006, Jakarta
Depkes RI, 2009, Riset Kesehatan
Dasar;RISKESDAS, Balitbang
Kemenkes RI, Jakarta.
Haluang, O., Tjitrosantoso, H., Kojong, N.
S., 2015, Analisis Biaya Penggunaan
Antibiotic Pada Penderita Demam
Tifoid Anak Di Instalasi Rawat Inap
RSUP Prof. DR. R.D. Kandou
Manado Periode Januari 2013 – Juni
Pharmacon, Jurnal Ilmiah
Farmasi – UNSRAT, Vol. 4 No. 3
Agustus 2015 ISSN 2302 – 2493
Ibrahim, S., 2003, Klinik Keluarga Terapi
Demam, Jakarta: Progres.
Mansjoer, A., 2001, Kapita Selekta
Kedokteran, Jakarta: Media
Aesculapius.
Mubin, A. H., 2007, Panduan Praktis Ilmu
Penyakit Dalam Diagnosis Dan
Terapi, EGC, Jakarta.
Nadyah, 2014, Hubungan Faktor-Faktor
Yang Mempengaruhi Insidens
Penyakit Demam Tifoid Di
Kelurahan Samata Kecamatan
Somba Opu Kabupaten Gowa 2013,
Jurnal Kesehatan, Vol VII No.
/2014, Fakultas Ilmu Kesehatan Uin
Alauddin Makassar
Parry, C. M., Hien, T. T., Dougan, G.,
White, N. J., Farrar, J. J., 2002,
Typhoid Fever, The New Englan
Journal of Medicine, Vol. 347, No.
, p. 1770-82.
Pramitasari, O. P., 2013, Faktor Risiko
Kejadian Penyakit Demam Tifoid
Pada Penderita Yang Dirawat Di
Rumah Sakit Umum Daerah
Ungaran. Jurnal Kesehatan
Masyarakat Undip 2013 Volume 2
No. 1.
Raflizar dan Herawati, M. H., 2010.
Hubungan Faktor Determinan
Dengan Kejadian Tifoid Di Pulau
Jawa. Jurnal Ekologi Kesehatan
Vol.9 No 4, Desember 2010 : 1357-
Rampengan, 2008, Penyakit Infeksi Tropik
pada Anak, Penerbit Buku
Kedokteran EGC, Jakarta.
Rascati, K. I., Drmmond, M. F.,
Annemans, I., dan Davey, P. G.,
, Education
inPharmacoeconomies: an
Internasional Multidiciplinary View
(Review), Pharmaco-Economics
; 22: 139-47.
Soedarmo, S. S. P., Garna, H., Hadinegoro,
S. R. S., Satari, H. I., 2010, Buku
Ajar Infeksi dan Pediatri Tropis,
Edisi ke 2, Cetakan kedua, Jakarta:
Ikatan Dokter Anak Indonesia.
Soedarmo, S. S. P., Garna, H., Hadinegoro,
S. R. S., Satari, H. I., 2012, Buku
Ajar Infeksi dan Pediatri Tropis,
Edisi ke 2, Cetakan ketiga, Jakarta:
Ikatan Dokter Anak Indonesia.
Soedarto, 2009, Penyakit Menular di
Indonesia, Jakarta: CV Sagung Seto.
Soegijanto, S., 2002, Ilmu Penyakit Anak,
Diagnosis dan Penatalaksanaan,
Edisi 1, Jakarta: Selemba Medika
Sulastomo, 2003, Manajemen Kesehatan,
Gramedia Pustaka Utama, Jakarta
Vogenberg, F. R., 2001, Introduction to
Applied Pharmacoeconomics.
McGraw Hill Medical Publishing
Division, USA.
Walley, T., Haycox, A. dan Boland, A.,
, Pharmacoeconomics.
Churchill Livingstone, Inggris.
Widoyono, 2011, Penyakit Tropis
(Epidemiologi, Penularan,
Pencegahan dan
Pemberantasannya), Jakarta:
Erlangga.
World Health Organization, 2003,
Background Documents: The
Diagnosis, Treatment, And
Prevention Of Typhoid Fever, No. 7,
p 59-70
Zulkoni, A., 2010, Parasitologi,
Yogyakarta: Nuha Medika
1.png){kind=small}
