Antibacterial Activity Of Clay Mask From Houttuynia Cordata Leaves Extract Against Staphylococcus Aureus

  • Muhammad Ryan Radix Rahardhian Sekolah Tinggi Ilmu Farmasi Yayasan Pharmasi Semarang
Keywords: Houttuynia cordata Thunb, Amis-amisan, Staphylococcus aureus, face scrub, antibacterial

Abstract

Facial skin that often looks dull and not glowing can be caused by the accumulation of dead skin cells. The solution to this problem is to exfoliate using a scrub. The content of secondary metabolites in Amis-amisan leaves (Houttuynia cordata Thunb) has antibacterial activity. This study aimed to determine the antibacterial activity of the face scrub ethanol extract of amis-amisan leaves against Staphylococcus aureus. The extract was obtained using the remaceration method using 96% ethanol. Concentrations of face scrub are 10%, 20%, and 30%. Antibacterial activity using the pour plate method. The results antibacterial activity of face scrub with concentrations of 10%, 20%, and 30%  are 1.127 cm, 1.282 cm and 1.460 cm, respectively. The best antibacterial activity is a 30% concentration face scrub. The physical characteristics of the organoleptic, homogeneity, pH, spreadability, adhesion, and irritation tests of the face scrub meet the specified requirements.

References

Abna, IM 2017. Microbiology and

Parasitology Practicum Guide. Esa

Unggul University, 30.

Agustini, L., Lukmani, Y., and Syafnir, L.

Literature Review of

Antibacterial Activity of Three Types

of Basil Leaf Extract (Ocimum

americanum L., Ocimum basilicum L.

and Ocimum sanctum L.) against

Acne-Causing Bacteria.

Pharmaceutical Proceedings, 2: 243–

Dian, S., Kusumawardhani, E., Artea, C.,

Haya, F., and Mask, C. 2022. Clay

Mask Papilak (Mussaenda frondosa L.)

against Bacteria That Cause Acne

No Activity F 1 F II F III Conclusion

Organoleptic Semi-solid Semi-solid Semi-solid

Color Green Green Green √

Smell Typical

Extracts

Typical

Extracts

Typical

Extracts

Homogeneity Homogeneous Homogeneous Homogeneous √

pH 6,668 5,408 4,706 √

Dispersion 5,210 5,342 5,508 √

Adhesion 5 seconds 6 seconds 7 seconds √

Irritation No symptoms

of irritation

No symptoms

of irritation

No symptoms

of irritation √

Viscosity 11.576 10.806 9.154 √

Vulgaris. Journal of Pharmaceutical

Sciences, 3: 110–117.

Fu, J., Dai, L., Lin, Z., and Lu, H. 2013.

Houttuynia cordataThunb : Review of

Phytochemistry and Pharmacology and

Quality Control. Journal of Scientific

Research, 4: 101-123.

Handayani, F.W., Muhtadi, A., Pharmacy,

F., Padjadjaran, U., Dara, T., Manis,

K., et al. 2013. Review Article :

Antibacterial Activity of Mangosteen

Peel Extract (Garcinia Mangostana L.)

Against acne-causing bacteria.

Farmaka, 4: 322–328.

Harborne, JB 1987. Phytochemical

methods. Second edition. ITB.

:Bandung.

Harry, Raph. G. (2000). Harry's

Cosmeticology. The Principle and

Practice of Modern Cosmetic, 8th

Edition. Chemical Publishing Co., Inc.

New York.

Laras, A.A.I.., Swastini, D.., Wardana, M.,

and Wijayanti, N.P.A.. 2014.

Irritation Test of Mangosteen Peel

Ethanol Extract (Garcinia mangostana

L.). Udayana Journal of Pharmacy, 3:

Marjoni, M. R. 2016. Fundamentals of

phytochemistry for diploma III

pharmacy. Pages 6-10. Jakarta : Trans

Info Media.

Miyata, M., Koyama, T., Science, U.,

Tokyo, K., and Co., S. 2010. Water

Extract of Houttuynia cordataThunb.

The Leaves Provide Anti-Obesity

Effects by Inhibiting the Absorption of

Fatty Acids and Glycerol. J Nutr Sci

Vitaminol, 56 : 150–156.

Ngajow, M., Abidjulu, J., and Kamu, V.S.

Antibacterial Effect of Matoa

Bark Extract (Pometia pinnata)

against Staphylococcus aureus

Bacteria In vitro. Journal of Mipa, 2:

Pratasik, M.C.M., Yamlean, P.V.Y., and

Wiyono, W.I. 2019. Formulation and

physical stability test of Sesewanua

leaf ethanol extract cream preparation

(Clerodendron squamatum Vahl.).

Pharmacon, 8: 261.

Putriani, K., Mardhiyani, D., Anggraini, L.,

and Abdurrab, U. 2022. Evaluation of

the peel-off gel preparation

combination of mango bacang leaf

extract (Mangifera foetida) and bay

leaf (Syzygium polyanthum)

Evaluation of the peel-off gel mask

preparation combination of mango

bacang (Mangifera foetida) and bay

leaf extract (Indonesian Journal of

Pharmaceutical Research, 4: 111–123.

Retnaningsih, A., Primadiamanti, A., and

Febrianti, A. 2019. Test of Inhibition

of Purple Leaf Ethanol Extract

(Graptophyllum pictum (L.) Griff)

Against Staphylococcus Epidermidis

Bacteria and Propionibacterium Acnes

Bacteria That Cause Acne by Disc

Method. Journal of Pharmaceutical

Analysts, 4:1–9.

Rosmania, R. and Yanti, F. 2020.

Calculation of the number of bacteria

in the Microbiology Laboratory using

the development of

spectrophotometric methods. Journal

of Science Research, 22: 76.

Published
2024-04-05
How to Cite
Rahardhian, M. R. R. (2024). Antibacterial Activity Of Clay Mask From Houttuynia Cordata Leaves Extract Against Staphylococcus Aureus . Media Farmasi Indonesia, 19(1). https://doi.org/10.53359/mfi.v19i1.228