KARAKTERISTIK FISIK DAN INDEKS IRITASI PADA SEDIAAN SHOOTING GEL KOMBINASI LIDAH BUAYADAN BUAH ANGGUR

  • Ririn Suharsanti
  • Lilies Wahyu Ariyani
Keywords: shooting gel, Aloe vera, grape fruit, physical characteristics, irritation test

Abstract

ABSTRACT

Shooting gel is one of cosmetic preparations that work to overcome dry skin. High active ingredients in shooting gel are considered able to rehydrate the skin, especially dry skin. In this research will be formulated shooting gel preparation with active ingredients ofAloe vera and grapes. The famous Aloe vera helps to moisturize the skin while the grapes also contain active compounds that are efficacious as antioxidants that are good for the skin. Therefore, the combination of these two active ingredients should be developed on the shooting gel preparation. This study aims to see the spread, stickiness, pH, viscosity, irritation of shooting gel with variations of concentration of active ingredients of Aloe vera and grapes. This research was started with formulation of shooting gel preparation with combination concentration of active ingredient 80% (FI); 85% (FII); 90% (FIII). Shooting gel is evaluated physical characteristics with parameters spreadibility, adhesivity,viscosity and pH. It was also evaluated the irritation index of the skin using male rats. The data obtained were analyzed with different 95% confidence level test to know the existence of significant difference between treatment groups. The experimental results of shooting gel physical characteristics showed that the concentration variation did not affect the adhesivity (p> 0.05) but affects pH, viscosity and spreadibility (p <0.05). Shooting gel with all three concentrations did not irritate the skin of male rats.

References

Aubert, C., Chalot, G., 2018. Chemical

composition, bioactive compounds,

and volatiles of six table grape

varieties (Vitis vinifera L.). Food

Chem. 240, 524–533.

Bachhav, Y., Patravale, V., 2010.

Formulation of meloxicam gel for

topical application: In vitro and in

vivo evaluation. Acta Pharm 60,

–163.

Bhinge, S.D., Bhutkar, M.A., Randive,

D.S., Wadkar, G.H., Todkar, S.S.,

Kakade, P.M., Kadam, P.M., 2017.

Formulation development and

evaluation of antimicrobial

polyherbal gel. Ann. Pharm. Fr. 75,

–358.

Javed, S., Atta-ur-Rahman, 2014. Chapter

- Aloe Vera Gel in Food, Health

Products, and Cosmetics Industry, in:

Atta-ur-Rahman (Ed.), Studies in

Natural Products Chemistry.

Elsevier, pp. 261–285.

Kuncari, E.S., Iskandarsyah, I., Praptiwi,

P., 2015. Uji Iritasi dan Aktivitas

Pertumbuhan Rambut Tikus Putih

:Efek Sediaan Gel Apigenin Dan

Perasan Herba Seledri (Apium

graveolens L.). Media Penelit. Dan

Pengemb. Kesehat. 25, 15–22.

Latifah, F., Sugihartini, N., Yuwono, T.,

Evaluation Of Physical

Properties And Irritation Index Og

Lotion Containing Syzigium

aromaticum Clove Essential Oil At

Various Concentration. Maj. Obat

Tradis. Tradit. Med. J. 21, 1–5.

Maan, A.A., Nazir, A., Khan, M.K.I.,

Ahmad, T., Zia, R., Murid, M.,

Abrar, M., 2018. The therapeutic

properties and applications of aloe

vera: a review. J. Herb. Med.

Safriani, R., Sugihartini, N., Yuliani, S.,

Physical characteristic and

irritation index of Syzigium

aromaticum essential oil in O/W and

W/O creams. IOP Conf. Ser. Mater.

Sci. Eng. 259, 012005.

Sinko, P.., 2006. Physical Chemical and

Biopharmaceutical Principles in The

Pharmaceutical Science, 5th ed.

Lippincott Williams and Wilkins,

Philadelphia.

Ulaen, Selfie, P.., Banne, Suatan, Y., Ririn,

A., 2012. Pembuatan Salep Anti

Jerawat dari Ekstrak Rimpang

Temulawak (Curcuma xanthorrhiza

Roxb.). J. Ilm. Farm. 3, 45–49.

Published
2018-03-01
How to Cite
Suharsanti, R., & Ariyani, L. W. (2018). KARAKTERISTIK FISIK DAN INDEKS IRITASI PADA SEDIAAN SHOOTING GEL KOMBINASI LIDAH BUAYADAN BUAH ANGGUR. Media Farmasi Indonesia, 13(1). Retrieved from https://mfi.stifar.ac.id/MFI/article/view/39